Modern researches indicate deficiency of kidney-yang has relation with the disorders of nerves-endocrine system (especially disorders of hormone secretion), and decreased immunological function. Many diseases, such as hypofunction in sex, sterility, osteoporosis in elder, dropsical nephritis, anaemia and aleucocytosis, occur for it.

The western medicines for deficiency of kidney-yang always have certain poison and side effect. But the diseases need long-term treatment. For example, long-term usage of sexual hormone for hypofunction in sex and sterility will aggravate the disorders in endocrine system. For another example, Ferrous Sulfate, an antianemia drugs, will stimulate gastric mucosa. Long-term intake will lead to stomach discomfort or diseases.

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